Supplementary Data for Benn et al., J Neurosci 2008, Huntingtin modulates

Relationship of transcription factors
with increased activity and gene expression changes

Supplementary Data for Benn et al., J Neurosci 2008 Huntingtin modulates transcription, occupies gene promoters in vivo and binds directly to DNA in a polyglutamine-dependent manner.

Relationship of transcription factors with increased activity and gene expression changes. *Interaction networks from Bibliosphere co-citations literature mining (Genomatix) show the input genes with changed mRNA expression (blue box) and their co-cited related transcription factor (white box) and their expression pathways (yellow box). Green lines represent transcription factor binding site on the gene promoter. Shown are:

Figure 1: (A) Absent in STHdh^7/7, Present in STHdh^111/111	Figure 3: (C) Present in both, down-regulated in STHdh^111/111
Figure 2: (B) Present in STHdh^7/7, Absent in STHdh^111/111	Figure 4: (D) Present in both, up-regulated in STHdh^111/111

Figure 1: (A) Absent in STHdh^7/7, Present in STHdh^111/111

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