Instructor, Harvard Medical School
Lab Phone: 617-726-6389
Charles (Chuck) Vanderburg is one of two Clinical Research Scientists in the MGH Department of Neurology’s teaching triad. As the director of the Harvard NeuroDiscovery Center’s Advanced Tissue Resource Core (ATRC) for the past twelve years, he has had an opportunity to work closely with many hundreds of neuroscientists in the Boston academic and biomedical research community. This broad exposure enables him to serve as a unique resource in the teaching triad’s endeavor to integrate clinical neurology with research neuroscience. Dr. Vanderburg is an instructor of Neurology at Harvard Medical School, Assistant Neurologist at Massachusetts General Hospital, and Adjunct Associate Professor at the MGH Institute of Health Professions. At the MGH Institute he was a founding faculty member of the Center for Interprofessional Studies and Innovation where he initiated distance learning and educational technology programs for allied health professionals. Dr. Vanderburg’s ATRC core laboratory provides technical expertise in the microgenomic and microproteomic profiling of human neuropathological tissue specimens and their derivatives using laser capture microdissection, digital PCR, multiplex bead cytometry, array-based expression analysis and Next-Gen Sequencing. His current research projects focus on non-coding RNAs and microvesicles as epigenetic regulators of neurodegenerative, neuromuscular and neuropsychiatric diseases.
Chuck holds a bachelor’s degree in biochemistry from the University of Pittsburgh, a masters degree in Immunology from Seton Hall University and a Ph.D. in anatomy, cellular, and molecular biology from New Jersey Medical School. Since completing his post-doctoral fellowship in developmental biology with Elizabeth Hay at Harvard Medical School, Chuck has served as a research program analyst at Massachusetts General Hospital, an adjunct associate professor at the MGH Institute of Health Professions, and a research scientist for NASA. He has been director of the ATRC laboratory at MIND since 2002.
- Meredith G. Banigan, Patricia F. Kao, James A. Kozubek, Ashley R. Winslow, Ozge Cagsal-Getkin, Juan Medina, Joan Costa, Andrea Schmitt, Howard Cabral, Ivana Delalle and Charles R. Vanderburg. Differential expression of exosomal miRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. PloS One 2013 8(1):e48814 PMID: 23382797
- Charles R. Vanderburg and Mark S.F. Clarke. Laser Microdissection of Metachromatically Stained Skeletal Muscle Allows Quantification of Fiber Type Specific Gene and Protein Expression. Mol Cell Biochem. 2013 Mar; 375(1-2):159-70. PMID:23196635
- Hon-Kit, Andus Wong, Tatiana Veremeyko, Nehal Patel, Christine Esau, Charles R. Vanderburg and Anna M. Krichevsky. De-repression of FOXO3a death axis by microRNA-132 causes neuronal apoptosis in Alzheimer’s disease. Human Molecular Genetics 2013 April (10) 1064-73 PMID: 23585551