MassGeneral Institute for Neurodegenerative Disease

Translating today's discoveries into tomorrow's cures

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Albers, Mark, MD, PhD

Biography
Affiliations

The sense of smell may provide important clues to help identify patients with neurodegenerative diseases before their symptoms emerge. Mark Albers uses the olfactory system of mice and humans to help understand the early events of neurodegeneration in order to find ways to intervene early in the disease process before symptoms appear and distinguish early pathologic events from changes produced by aging. His lab combines molecular biological, anatomical, physiological, imaging,and behavioral techniques to learn about genes associated with neurodegenerative disease.

Sadri-Vakili,Ghazaleh, PhD

Biography
Affiliations

The NeuroEpigenetics laboratory at MIND, under the direction of Ghazaleh Sadri-Vakili studies the molecular mechanisms that underlie alterations in gene expression in disorders of the nervous system using the most current molecular biology tools. Currently, their efforts are focused on Huntington’s disease (HD), Amyotrophic Lateral Sclerosis (ALS), as well as addiction.

Berezovska, Oksana, PhD

Biography
Affiliations

Oksana Berezovska leads the Neurobilogy of Alzheimer’s disease research laboratory that studies cellular and molecular events leading to neuropathological changes in Alzheimer’s disease, with a particular focus on the synapse. The ratio of amyloid beta peptides that end in amino acid 42 as compared to amino acid 40 can be measured in the cerebrospinal fluid. An increase in the Abeta 42/40 ratio has been implicated in Alzheimer's disease (AD) pathogenesis.

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