MassGeneral Institute for Neurodegenerative Disease

Translating today's discoveries into tomorrow's cures

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Ozelius, Laurie, PhD

Biography
Affiliations

Laurie Ozelius works to uncover genetic causes for movement disorders, especially dystonias and Parkinson’s disease. Dystonias are characterized by involuntary muscle contractions that lead to slow movements or abnormal postures. Dystonias can be localized, as in writers’ cramp or torticollis, or generalized, and they often run in families.

Chen, Xiqun, MD, PhD

Biography
Affiliations

Trained in clinical and basic neuroscience, Xiqun Chen studies the molecular biology of neurodegeneration in Parkinson’s disease (PD) and related disorders. Working with collaborators at MGH, the Harvard School of Public Health, and overseas, Chen’s group is pursuing the biological basis of the epidemiological link between PD and melanoma.  Studies have shown that Parkinson’s patients have a higher incidence of melanoma, and that melanoma patients have a higher risk of developing PD.

Suh, Jaehong, PhD

Biography
Affiliations

Dr. Jaehong Suh studies the genetic and molecular mechanisms of Alzheimer’s disease (AD) and other neurodegenerative disorders, with the aim of identifying novel therapeutic targets and developing effective treatments for patients. Suh was involved in the identification of novel mutations from late-onset AD families in the prodomain of ADAM10, a major a-secretase that cleaves B-amyloid (AB region of amyloid precursor protein (APP).

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