MassGeneral Institute for Neurodegenerative Disease

Translating today's discoveries into tomorrow's cures

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Wasco, Wilma, PhD

Biography
Affiliations

Wilma Wasco is interested in factors and events that surround the neuronal degeneration that is characteristic of Alzheimer's disease and normal aging. Her lab was involved in the identification and characterization the two presenilin proteins (PS1 and PS2), and her current focus is on identifying genes associated with the etiology of late onset Alzheimer’s disease.

Albers, Mark, MD, PhD

Biography
Affiliations

The sense of smell may provide important clues to help identify patients with neurodegenerative diseases before their symptoms emerge. Mark Albers uses the olfactory system of mice and humans to help understand the early events of neurodegeneration in order to find ways to intervene early in the disease process before symptoms appear and distinguish early pathologic events from changes produced by aging. His lab combines molecular biological, anatomical, physiological, imaging,and behavioral techniques to learn about genes associated with neurodegenerative disease.

Clark, Tim, PhD

Biography
Affiliations

Tim Clark is an Assistant Professor of Neurology at Harvard Medical School and Director of the Biomedical Informatics Research Core at the Massachusetts General Hospital. He also serves on the Executive Committee of the Massachusetts Alzheimer Disease Research Center, where he co-directs the Data and Statistics Core. His current research focus is on bio- and neuro-informatics, scientific social media, web annotation, and next-generation scientific publishing using semantic technologies.

Biography

Vanderburg, Charles, PhD

Biography
Affiliations

Charles (Chuck) Vanderburg is one of two Clinical Research Scientists in the MGH Department of Neurology’s teaching triad. As the director of the Harvard NeuroDiscovery Center’s Advanced Tissue Resource Core (ATRC) for the past twelve years, he has had an opportunity to work closely with many hundreds of neuroscientists in the Boston academic and biomedical research community. This broad exposure enables him to serve as a unique resource in the teaching triad’s endeavor to integrate clinical neurology with research neuroscience. Dr.

Sadri-Vakili,Ghazaleh, PhD

Biography
Affiliations

The NeuroEpigenetics laboratory at MIND, under the direction of Ghazaleh Sadri-Vakili studies the molecular mechanisms that underlie alterations in gene expression in disorders of the nervous system using the most current molecular biology tools. Currently, their efforts are focused on Huntington’s disease (HD), Amyotrophic Lateral Sclerosis (ALS), as well as addiction.

Berezovska, Oksana, PhD

Biography
Affiliations

Oksana Berezovska leads the Neurobilogy of Alzheimer’s disease research laboratory that studies cellular and molecular events leading to neuropathological changes in Alzheimer’s disease, with a particular focus on the synapse. The ratio of amyloid beta peptides that end in amino acid 42 as compared to amino acid 40 can be measured in the cerebrospinal fluid. An increase in the Abeta 42/40 ratio has been implicated in Alzheimer's disease (AD) pathogenesis.

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