MassGeneral Institute for Neurodegenerative Disease

Translating today's discoveries into tomorrow's cures

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DiFiglia, Marian, PhD

Biography
Affiliations

Marian DiFiglia is a Professor of Neurology at Harvard Medical School and Director of the Laboratory of Cellular Neurobiology at MassGeneral Institute for Neurodegenerative Disease. Sheleads a multidisciplinary research team investigating the role of the Huntington’s disease mutation in the molecular and cellular events leading to neurodegeneration in Huntington’s disease (HD).

Schwarzschild, Michael, MD, PhD

Biography
Affiliations

Michael Schwarzschild's lab investigates molecular mechanisms in mouse models of Parkinson’s disease in an effort to develop improved therapies for neurodegenerative diseases. His research extends to the clinic where he conducts trials of novel treatments with the potential to slow progression of Parkinson’s disease. The Schwarzschild lab focuses on a natural class of compounds known as purines, in particular the role of purines — adenosine, caffeine, inosine and urate — and how targeting them may prevent or slow the brain cell degeneration of Parkinson’s.

Hersch, Steven, MD, PhD

Biography
Affiliations

Steven Hersch’s research focuses on Huntington’s disease (HD) and helping to develop treatments to slow or cure this fatal progressive neurogenetic disorder. His laboratory works to discover and translate potential disease modifying therapies and biomarkers from the lab to the clinic.

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